Description
Product Characteristics:
Transcriptional activator that acts at a palindromic recognition sequence to enhance the activity of the SV40 and TK promoters. Functions as a repressor with the prolactin promoter in vivo. May play a role in chondrocyte differentiation and may also influence cervix development.
Subcellular location: Nucleus
Synonyms: ALX homeobox 1, ALX homeobox protein 1, ALX1, ALX1_HUMAN, CART 1, CART-1, CART1, Cartilage homeoprotein 1.
Target Information: The specific function of this gene has yet to be determined in humans\, however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly. [provided by RefSeq, Jul 2008]